以下乃搜尋自google的說明
裡面大義是此藥是作用在腦細胞間抑制dopamine的敏感度,
主要用來治療內耳疾病,精神疾病之焦慮,精神分裂,和噁心與嘔吐。
未提及高山症之適用。
不知是否有新用途,或新的臨床效用。還請其他前輩提供經驗。
How does it work?
Prochlorperazine belongs to a group of medications known as the phenothiazine antipsychotics. It is sometimes referred to as a 'major tranquilliser'. It acts by blocking a variety of receptors in the brain, particularly dopamine receptors. Dopamine is involved in transmitting signals between brain cells. When there is an excess amount of dopamine in the brain it causes over-stimulation of dopamine receptors. These receptors normally act to modify behaviour and over-stimulation may result in psychotic illness. Prochlorperazine blocks these receptors and stops them becoming over-stimulated, thereby helping to control psychotic illness. Although prochlorperazine can be used in the control of psychotic conditions such as schizophrenia, it also affects receptors in an area of the brain that controls nausea and vomiting. For this reason, it is also useful in the treatment of nausea and vomiting, especially when it is caused by medication or radiation treatment. Prochlorperazine is also used to control symptoms such as nausea and dizziness which are caused by inner ear disorders.
What is it used for?
Anxiety (short term use)
Disorders of the inner ear
Mania
Meniere's disease
Nausea and vomiting
Psychotic illness
Schizophrenia
Warning!
Do not drink alcohol whilst taking this medicine.
Use with caution in
Abnormal heart rhythm seen on the heart monitoring trace (ECG) as a 'prolonged QT interval'
Abnormal muscle weakness
Closed angle glaucoma
Elderly people
Enlarged prostate gland
Epilepsy
Hypothyroidism
Kidney disease
Liver disease
Low blood potassium levels (hypokalaemia)
Parkinson's disease
Tumour of the adrenal gland (phaeochromocytoma)
Not to be used in